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Ceylon Cinnamon | (Cinnamomum verum) |
-analysis by Ranasinghe, et al. and a systematic review by Bandara et al., on the effects of CZ extracts on diabetes demonstrates numerous beneficial effects both in-vitro and in-vivo. In-vitro CZ has demonstrated a potential for; a) reducing post-prandial intestinal glucose absorption by inhibiting the activity of enzymes involved in carbohydrate metabolism (pancreatic α–amylase and α–glucosidase), b) stimulating cellular glucose uptake by membrane translocation of GLUT-4, c) stimulating glucose metabolism and glycogen synthesis, d) inhibiting gluconeogenesis by effects on key regulatory enzymes and f) stimulating insulin release and potentiating insulin receptor activity.
Cinnamtannin B1 was identified as the potential active compound responsible for these effects.